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PVP

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Non-reproductive organ system toxicity (moderate)

Cancer

Developmental & Reproductive Toxicity

Allergies & Immunotoxicity

Products with this Ingredient

hair styling aide 159 products
mascara 132 products
styling gel/lotion 91 products
brow liner 53 products
tooth whitening 50 products
setting powder/spray 48 products
mask 44 products
eye liner 38 products
eye shadow 28 products
makeup primer 27 products
shaving cream 24 products
foundation 24 products
conditioner 23 products
styling mousse/foam 22 products
hair spray 21 products
toothpaste 20 products
concealer 19 products
hair color and bleaching 18 products
facial moisturizer/treatment 17 products
glitter 16 products
serums & essences 16 products
hair treatment/serum 14 products
shampoo 12 products
bath oil/salts/soak 7 products
shaving cream (men's) 7 products
beard care 6 products
daily use with SPF 6 products
moisturizer 5 products
pore strips 5 products
lipstick 5 products
BB cream 5 products
recreational sunscreen 4 products
facial cleanser 4 products
exfoliant/scrub 4 products
detangler 3 products
toners/astringents 3 products
other eye makeup 3 products
eye makeup remover 2 products
around-eye cream 2 products
1 products
anti-aging 1 products
oil controller 1 products
eyelash glue 1 products
bronzer/highlighter 1 products

Organ system toxicity (non-reproductive)

Concern Reference
Classified as expected to be toxic or harmful Environment Canada Domestic Substance List
Classified as medium human health priority Environment Canada Domestic Substance List

Data gaps

Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product Cosmetic Ingredient Review Assessments
13470 studies in PubMed science library may include information on the toxicity of this chemical NLM PubMed

Cancer

Concern Reference
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gaps World Health Organization, International Agency for Research on Cancer IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans. Lists of Group 1, 2a, and 2b substances can be obtained. http://monographs.iarc.fr/ENG/Classification/index.php; Vol 19, Suppl. 7, 71 ;1987

Ecotoxicology

Concern Reference
Not suspected to be an environmental toxin Environment Canada Domestic Substance List

Multiple, additive exposure sources

Concern Reference
Designated as safe for general or specific, limited use in food FDA Food Additive Status
Designated as safe for general or specific, limited use in food FDA Everything Added to Food

Informational

Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any Cosmetic Ingredient Review Assessments

Persistence and bioaccumulation

Concern Reference
Not suspected to be bioaccumulative Environment Canada Domestic Substance List

Data Sources

  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • World Health Organization, International Agency for Research on Cancer IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans. Lists of Group 1, 2a, and 2b substances can be obtained. http://monographs.iarc.fr/ENG/Classification/index.php; Vol 19, Suppl. 7, 71 ;1987
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

ABOUT THE SKIN DEEP® RATINGS

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